The EBV nuclear antigen 1 (EBNA1) enhances B cell immortalization several thousandfold
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چکیده
منابع مشابه
The EBV nuclear antigen 1 (EBNA1) enhances B cell immortalization several thousandfold.
The Epstein-Barr virus (EBV) nuclear antigen 1 (EBNA1) is one of the earliest viral proteins expressed after infection and is the only latent protein consistently expressed in viral-associated tumors. EBNA1's crucial role in viral DNA replication, episomal maintenance, and partitioning is well examined whereas its importance for the immortalization process and the tumorgenicity of EBV is unclea...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2003
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1832776100